GP161 Polyclonal Antibody, 50ul Thermo Mix It plays a negative regulatory

It plays a negative regulatory role in the Ras-Raf1-MAPK pathway

it has been demonstrated that GALR2 couples efficiently to both the Gq and Gi proteins to simul

It may play a role in T-cell-B-cell interactions

including cell division control protein 42 (CDC42) and the actin-related protein-2/3 (ARP2/3) complex

including those that are involved in familial adenomatous polyposis

GP161 Polyclonal Antibody, 50ul Thermo Mix It plays a negative regulatoryUpon ligand binding, G protein coupled receptors, such as GPR161, activate cytoplasmic G proteins (see GNAS, MIM 139320), allowing the receptors to transduce extracellular signals across the plasma membrane into the cell. Phosphorylation of the receptor attenuates signaling (Matteson et al., 2008