TNF-IP 8 Polyclonal Antibody, 20ul Variant Libraries Receptor tyrosine-protein kinase erbB-2 has

Receptor tyrosine-protein kinase erbB-2 has no ligand binding domain of its own and therefore cannot bind growth factors

A long isoform of the protein has an N-terminal domain that is homologous to the extracellular part of frizzled receptors

which belongs to the superfamily of intermediate filament (IF) proteins

a complex of the mitochondrial respiratory chain

It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes

TNF-IP 8 Polyclonal Antibody, 20ul Variant Libraries Receptor tyrosine-protein kinase erbB-2 hasTNFAIP8 (TNF Alpha Induced Protein 8) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include cysteine type endopeptidase inhibitor activity involved in apoptotic process. An important paralog of this gene is TNFAIP8L2. Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF mediated apoptosis by inhibiting caspase 8 activity but not the processing of procaspase 8,