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ErbB-3 Polyclonal Antibody, 20ul[BT-AP03043] Funnels a recessively inherited connective-tissue disorder

SKU: 98629880303

4.5
EUR97.20 EUR129.20

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ErbB-3 Polyclonal Antibody, 20ul[BT-AP03043] Funnels a recessively inherited connective-tissue disorderERBB3 encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation

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Description

a recessively inherited connective-tissue disorder

Its role in the regulation of normal mitochondrial function and in disease states attributed to mitochondrial dysfunction is not known

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ErbB-3 Polyclonal Antibody, 20ul[BT-AP03043] Funnels a recessively inherited connective-tissue disorderERBB3 encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation

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