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SRGN Rabbit Polyclonal Antibody, 100ul Cell Labeling & Imaging Phosphorylation is enhanced upon serum

SKU: 98190343698

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SRGN Rabbit Polyclonal Antibody, 100ul Cell Labeling & Imaging Phosphorylation is enhanced upon serumThis gene encodes a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease resistant peptide core which may be important for neutralizing hydrolytic enzymes. This encoded protein was found to be associated with the macromolecular complex of granzymes and perforin which may serve as a mediator of granule mediated apoptosis. Two transcript

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Description

Phosphorylation is enhanced upon serum stimulation

tissue specificity:Predominantly expressed in neurons of adult and fetal brain

Alternatively spliced transcript variants encoding the same protein have been observed

Interacts with RNF7/RBX2

This gene is localized to chromosome 8q22 which is disrupted in a variety of cancers

SRGN Rabbit Polyclonal Antibody, 100ul Cell Labeling & Imaging Phosphorylation is enhanced upon serumThis gene encodes a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease resistant peptide core which may be important for neutralizing hydrolytic enzymes. This encoded protein was found to be associated with the macromolecular complex of granzymes and perforin which may serve as a mediator of granule mediated apoptosis. Two transcript

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