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NPT2b Polyclonal Antibody, 50ul Microbial Genome Editing Core component of multiple SCF-like

SKU: 97882860517

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NPT2b Polyclonal Antibody, 50ul Microbial Genome Editing Core component of multiple SCF-likeSodium dependent phosphate transport protein 2B encoded by SLC34A2 is a pH sensitive sodium dependent phosphate transporter. Phosphate uptake is increased at lower pH. Defects in this gene are a cause of pulmonary alveolar microlithiasis. Three transcript variants encoding two different isoforms have been found for this gene.

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Description

Core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes

The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis

The heterodimer formed with GATA proteins is essential to activate expression of genes such as NFE2

PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth| differentiation| mitotic cycle| and oncogenic transformation

This protein is localized in the nucleus and contains an E1A-type zinc finger domain

NPT2b Polyclonal Antibody, 50ul Microbial Genome Editing Core component of multiple SCF-likeSodium dependent phosphate transport protein 2B encoded by SLC34A2 is a pH sensitive sodium dependent phosphate transporter. Phosphate uptake is increased at lower pH. Defects in this gene are a cause of pulmonary alveolar microlithiasis. Three transcript variants encoding two different isoforms have been found for this gene.

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