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HUS1 Polyclonal Antibody, 100ul sgRNA Library Construction VASP is regulated by the

SKU: 97705769517

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EUR141.00 EUR185.00

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HUS1 Polyclonal Antibody, 100ul sgRNA Library Construction VASP is regulated by theThe protein encoded by this gene is a component of an evolutionarily conserved, genotoxin activated checkpoint complex that is involved in the cell cycle arrest in response to DNA damage. This protein forms a heterotrimeric complex with checkpoint proteins RAD9 and RAD1. In response to DNA damage, the trimeric complex interacts with another protein complex consisting of checkpoint protein RAD17 and four small subunits of the replication factor C

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Description

VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG

Contains 6 LRR (leucine-rich) repeats

and may play a role in the inhibition of tumor transformation and progression of several malignancies including lung cancer

The protein encoded by AXL (AXL receptor tyrosine kinase) is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily

which binds to one of the components of the multiprotein editosome complex

HUS1 Polyclonal Antibody, 100ul sgRNA Library Construction VASP is regulated by theThe protein encoded by this gene is a component of an evolutionarily conserved, genotoxin activated checkpoint complex that is involved in the cell cycle arrest in response to DNA damage. This protein forms a heterotrimeric complex with checkpoint proteins RAD9 and RAD1. In response to DNA damage, the trimeric complex interacts with another protein complex consisting of checkpoint protein RAD17 and four small subunits of the replication factor C

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