MAFK Polyclonal Antibody, 20ul In vitro Assessment Both alpha and beta chains

Both alpha and beta chains share significant homology to immunoglobulin variable light chains

Mutations in this gene cause combined oxidative phosphorylation deficiency 6 (COXPD6)

and besides AGE

C8 participates in the formation of the membrane attack complex (MAC)

Primary glomerulonephritis with immune deposits and age-related macular degeneration are other conditions associated with mutations of this gene

MAFK Polyclonal Antibody, 20ul In vitro Assessment Both alpha and beta chainsThe developmentally regulated expression of the globin genes depends on upstream regulatory elements termed locus control regions (LCRs). LCRs are associated with powerful enhancer activity that is mediated by the transcription factor NFE2 (nuclear factor erythroid 2). NFE2 recognition sites are also present in the gene promoters of 2 heme biosynthetic enzymes, porphobilinogen deaminase (PBGD; MIM 609806) and ferrochelatase (FECH; MIM 612386). NFE2