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Insulin R Polyclonal Antibody, 100ul[BT-AP04566] Primary Antibodies Significantly overexpressed in many lung

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Insulin R Polyclonal Antibody, 100ul[BT-AP04566] Primary Antibodies Significantly overexpressed in many lungINSR encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the

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Description

Significantly overexpressed in many lung cancer samples

Proteins of this family are defined by a vacuolar protein sorting 10 domain at the N-terminus

SELP encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells

CDKN1B encodes a cyclin-dependent kinase inhibitor

The protein also plays a role in megakaryocytic cell maturation

Insulin R Polyclonal Antibody, 100ul[BT-AP04566] Primary Antibodies Significantly overexpressed in many lungINSR encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the

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