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PKC Theta Polyclonal Antibody, 20ul[BT-AP07222] Inoculating Loops/Needles The amino terminus of calreticulin

SKU: 97197487900

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PLN111.00 PLN143.00

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PKC Theta Polyclonal Antibody, 20ul[BT-AP07222] Inoculating Loops/Needles The amino terminus of calreticulinProtein kinase C (PKC) is a family of serine and threonine specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile

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Description

The amino terminus of calreticulin interacts with the DNA-binding domain of the glucocorticoid receptor and prevents the receptor from binding to its specific glucocorticoid response element

which is a member of the 7 transmembrane-spanning G protein-coupled receptor family

Defect in GIPR thus may contribute to the pathogenesis of diabetes

also known as PUMAG or Puma-g

This protein also interacts with the tumor suppressor P53 after exposure to cell stress

PKC Theta Polyclonal Antibody, 20ul[BT-AP07222] Inoculating Loops/Needles The amino terminus of calreticulinProtein kinase C (PKC) is a family of serine and threonine specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile

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