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HLA Class I Polyclonal Antibody, 100ul[BT-AP10062] Thermo Mix Alternative splicing of this gene

SKU: 97045001773

4.5
PLN123.75 PLN166.75

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HLA Class I Polyclonal Antibody, 100ul[BT-AP10062] Thermo Mix Alternative splicing of this geneHLA A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta 2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon

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Description

Alternative splicing of this gene generates three transcript variants encoding different isoforms

This protein may play a role in physiologic functions at mucosal sites

and it may also play a role in neuroimmune function

The coding region of this gene is intronless

A serine-rich region promotes activation of the serum response element (SRE)

HLA Class I Polyclonal Antibody, 100ul[BT-AP10062] Thermo Mix Alternative splicing of this geneHLA A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta 2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon

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