Phospho-Btk (Y223) Polyclonal Antibody, 20ul Adenovirus Packaging The P1 downstream promoter of
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Phospho-Btk (Y223) Polyclonal Antibody, 20ul Adenovirus Packaging The P1 downstream promoter ofBruton tyrosine kinase encoded by BTK plays a crucial role in B cell development. Mutations in BTK cause X linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.
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