Topoisomerase II alpha(Phospho-Ser1469) Rabbit Polyclonal Antibody, 100ul Virus Packaging Mutations in PEX1 have been

Mutations in PEX1 have been associated with complementation group 1 peroxisomal disorders such as neonatal adrenoleukodystrophy

This protein regulates Myotonic Dystrophy Protein Kinase

Alternative splicing results in multiple transcript variants encoding distinct protein isoforms

Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported

Binds to and inhibits cyclin-dependent kinase activity| preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression

Topoisomerase II alpha(Phospho-Ser1469) Rabbit Polyclonal Antibody, 100ul Virus Packaging Mutations in PEX1 have beenThis gene encodes a DNA topoisomerase an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation chromatid separation and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another thus altering