TPH2 Polyclonal Antibody, 20ul Liquid Storage Consumables Three transcript variants encoding two

Three transcript variants encoding two different isoforms have been found for this gene

RXFP3 (Relaxin/Insulin Like Family Peptide Receptor 3) is a Protein Coding gene

The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C

while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin

They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK

TPH2 Polyclonal Antibody, 20ul Liquid Storage Consumables Three transcript variants encoding twoTPH2 encodes a member of the pterin dependent aromatic acid hydroxylase family. The tryptophan hydroxylase 2 catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression.