IOD2 Polyclonal Antibody, 50ul Centrifuge Tube (Bottle) Mutations in SOS2 are associated

Mutations in SOS2 are associated with Noonan Syndrome-9

This gene is mutated in congenital disorder of glycosylation type Ik

and regulates centriole duplication during the cell cycle

AMBN encodes the nonamelogenin enamel matrix protein ameloblastin

and are involved in intracellular trafficking

IOD2 Polyclonal Antibody, 50ul Centrifuge Tube (Bottle) Mutations in SOS2 are associatedThe protein encoded by this gene belongs to the iodothyronine deiodinase family. It catalyzes the conversion of prohormone thyroxine (3,5,3',5' tetraiodothyronine, T4) to the bioactive thyroid hormone (3,5,3' triiodothyronine, T3) by outer ring 5' deiodination. This gene is widely expressed, including in thyroid, placenta, pituitary and brain. It is thought to be responsible for the 'local' production of T3, and thus important in influencing thyroid