MCLN2 Rabbit Polyclonal Antibody, 50ul Biomatrix This encoded protein is a

This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin

an essential protein required to the initiation of DNA replication

This enzyme forms a complex with BLM which functions in the regulation of recombination in somatic cells

Expression of this protein was reduced in human breast cancers while its overexpression reduced tumor growth and metastasis

transcription regulation

MCLN2 Rabbit Polyclonal Antibody, 50ul Biomatrix This encoded protein is aMucolipins constitute a family of cation channel proteins with homology to the transient receptor potential superfamily. In mammals the mucolipin family includes 3 members MCOLN1 (MIM 605248) MCOLN2 and MCOLN3 (MIM 607400) that exhibit a common 6 membrane spanning topology. Homologs of mammalian mucolipins exist in Drosophila and C. elegans. Mutations in the human MCOLN1 gene cause mucolipodosis IV (MIM 262650) (Karacsonyi et al. 2007