Smad2(Phospho Ser467) Polyclonal Antibody, 20ul Drying & Desiccation The mutL homolog 3 encoded

The mutL homolog 3 encoded by MLH3 functions as a heterodimer with other family members

which maps to chromosome 10p

chronic infantile neurological cutaneous and articular (CINCA) syndrome

Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia

and is involved in B-cell proliferation and immunoglobulin secretion

Smad2(Phospho Ser467) Polyclonal Antibody, 20ul Drying & Desiccation The mutL homolog 3 encodedThe protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signal of the transforming growth factor (TGF) beta, and thus regulates multiple cellular processes, such as cell