Stat5a Polyclonal Antibody, 50ul[BT-AP08639] Polyclonal Antibody Preparation and is specifically localized to

and is specifically localized to epithelial cells in skin

The TRIM motif includes three zinc-binding domains| a RING| a B-box type 1 and a B-box type 2| and a coiled-coil region

are the main components of the nuclear pore complex in eukaryotic cells

IL5 encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils

has a putative extracellular domain with five immunoglobulin (Ig)-like loops and three fibronectin (Fn) type III motifs

Stat5a Polyclonal Antibody, 50ul[BT-AP08639] Polyclonal Antibody Preparation and is specifically localized toStat5 is activated in response to a wide variety of ligands including IL 2, GM CSF, growth hormone and prolactin. Phosphorylation at Tyr694 is obligatory for Stat5 activation. This phosphorylation is mediated by Src upon erythropoietin stimulation. Stat5 is constitutively active in some leukemic cell types. Phosphorylated Stat5 is found in some endothelial cells treated with IL 3, which suggests its involvement in angiogenesis and cell motility.