Rat Insulin-like Growth Factors 1 Receptor, IGF-1R ELISA Kit, 96T DNA Fragments EBI3 was identified by its

EBI3 was identified by its induced expression in B lymphocytes in response Epstein-Barr virus infection

and inside the kinetochore corona

Also regulates the centrosome organization (PubMed: 18045989

The human engrailed homologs 1 and 2 encode homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system

It is also involved in oogenesis and in neuronal differentiation

Rat Insulin-like Growth Factors 1 Receptor, IGF-1R ELISA Kit, 96T DNA Fragments EBI3 was identified by itsReceptor tyrosine kinase which mediates actions of Insulin like growth factor 1 (IGF1). Binds IGF1 with high affinity and IGF2 and insulin (INS) with a lower affinity. The activated IGF1R is involved in cell growth and survival control. IGF1R is crucial for tumor transformation and survival of malignant cell. Ligand binding activates the receptor kinase, leading to receptor autophosphorylation, and tyrosines phosphorylation of multiple substrates,