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CD57 Polyclonal Antibody, 100ul[BT-AP02069] Cell Labeling & Imaging both of which are involved

SKU: 94442249072

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CD57 Polyclonal Antibody, 100ul[BT-AP02069] Cell Labeling & Imaging both of which are involvedCOL17A1 (collagen type XVII alpha 1 chain) encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in COL17A1 are associated with both generalized atrophic benign and junctional epidermolysis

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Description

both of which are involved in UV radiation induced apoptosis

Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder

The product of this gene is part of a protein complex that regulates the endocytosis of growth factor receptors

The predicted protein is proline-rich and contains several dopamine D4 receptor signatures and PRINTS domains

suggesting an important role of this protein during integrin-dependent cell adhesion

CD57 Polyclonal Antibody, 100ul[BT-AP02069] Cell Labeling & Imaging both of which are involvedCOL17A1 (collagen type XVII alpha 1 chain) encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in COL17A1 are associated with both generalized atrophic benign and junctional epidermolysis

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