RB27A Polyclonal Antibody, 100ul Centrifuges The protein is a giant

The protein is a giant scaffold and mosaic cyclophilin-related nucleoporin implicated in the Ran-GTPase cycle

HOXA1 is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression

the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation

and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts

SMUG1 encodes a protein that participates in base excision repair by removing uracil from single- and double-stranded DNA

RB27A Polyclonal Antibody, 100ul Centrifuges The protein is a giantThe protein encoded by this gene belongs to the small GTPase superfamily, Rab family. The protein is membrane bound and may be involved in protein transport and small GTPase mediated signal transduction. Mutations in this gene are associated with Griscelli syndrome type 2. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.