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MYH Polyclonal Antibody, 50ul sgRNA Oligos Mutations in this gene have

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MYH Polyclonal Antibody, 50ul sgRNA Oligos Mutations in this gene haveMUTYH encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8 oxo 7,8 dihydroguanine, a major oxidatively damaged DNA lesion. A G specific adenine DNA glycosylase is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple

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Description

Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP)

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or cellular calcium/phosphate homeostasis

GO annotations related to this gene include receptor activity and scavenger receptor activity

The encoded protein could be a spermatogenesis-specific component of the DNA-binding general transcription factor complex TFIID

MYH Polyclonal Antibody, 50ul sgRNA Oligos Mutations in this gene haveMUTYH encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8 oxo 7,8 dihydroguanine, a major oxidatively damaged DNA lesion. A G specific adenine DNA glycosylase is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple

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