Histone H3 Monoclonal Antibody, 50ul Liquid Handling ＆Storage SOCS family members are cytokine-inducible

SOCS family members are cytokine-inducible negative regulators of cytokine receptor signaling via the Janus kinase/signal transducer and activation of transcription pathway (the JAK/STAT pathway)

which facilitates cellular transformation

consisting of 6 transmembrane domains and a histidine-rich cytoplasmic loop

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PIM1 is expressed primarily in B-lymphoid and myeloid cell lines

Histone H3 Monoclonal Antibody, 50ul Liquid Handling ＆Storage SOCS family members are cytokine-inducibleHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin