GRK 2(Phospho Ser685) Polyclonal Antibody, 100ul Sampling Tubes and homeostasis by coupling chromatin

and homeostasis by coupling chromatin remodeling to transcription factor recognition

These proteins associate with Amphiphysin

Overexpression of this gene has been associated with acute myelocytic leukemia

Contains 1 thyroglobulin type-1 domain

Contains 1 IRS-type PTB domain

GRK 2(Phospho Ser685) Polyclonal Antibody, 100ul Sampling Tubes and homeostasis by coupling chromatinThe product of this gene phosphorylates the beta 2 adrenergic receptor and appears to mediate agonist specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta adrenergic and related G protein coupled receptors. Abnormal coupling of beta adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.