Rat Mothers Against Decapentaplegic Homolog 3, SMAD3 ELISA Kit, 96T DNA Fragments An important paralog of this

An important paralog of this gene is UBTD1

thereby increasing binding of transcriptional activator FOXO3 to the ESR1 promoter and increasing ESR1 transcription (PubMed: 21602804)

PubMed: 28887056

It also prevents telomere elongation by inhibiting the actions of telomerase

Cell surface proteoglycan that bears heparan sulfate

Rat Mothers Against Decapentaplegic Homolog 3, SMAD3 ELISA Kit, 96T DNA Fragments An important paralog of thisReceptor regulated SMAD (R SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF beta and, on formation of the SMAD3 SMAD4 complex, activates transcription. Also can form a SMAD3 SMAD4 JUN FOS complex at the AP 1 SMAD site to regulate TGF beta mediated