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Shb Polyclonal Antibody, 100ul[BT-AP08287] Palm Micro Centrifuges The interaction between this protein

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Shb Polyclonal Antibody, 100ul[BT-AP08287] Palm Micro Centrifuges The interaction between this proteinThe SH2 (Src Homology 2) domain is a structurally conserved motif that contains two alpha helices and seven beta strands and is found in a variety of proteins that are involved in signal transduction throughout the cell. Specifically, the SH2 domain targets SH2 domain containing proteins to tyrosine phosphorylated sites, an event that can trigger a protein protein interaction cascade which may ultimately effect gene expression and cellular function.

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Description

The interaction between this protein and beta1 integrin is highly specific

as well as JAK2 and TYK2 kinases

and for other syndromal and nonspecific forms of X-linked mental retardation mapping to this region

The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase

cAMP and cGMP function as key regulators of many important physiological processes

Shb Polyclonal Antibody, 100ul[BT-AP08287] Palm Micro Centrifuges The interaction between this proteinThe SH2 (Src Homology 2) domain is a structurally conserved motif that contains two alpha helices and seven beta strands and is found in a variety of proteins that are involved in signal transduction throughout the cell. Specifically, the SH2 domain targets SH2 domain containing proteins to tyrosine phosphorylated sites, an event that can trigger a protein protein interaction cascade which may ultimately effect gene expression and cellular function.

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