Tcl1 Polyclonal Antibody, 50ul Peripheral Blood Separation Tube KNG1 uses alternative splicing to

KNG1 uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK)

transcript variants originating from this position are expressed from the maternal allele

MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase| MAPK kinase/MEK| which in turn activates MAPK

Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits

Protein kinase C alpha by PRKCA is one of the PKC family members

Tcl1 Polyclonal Antibody, 50ul Peripheral Blood Separation Tube KNG1 uses alternative splicing toOverexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T cell antigen receptor (TCR) alpha (MIM 186880) or TCR beta (MIM 186930) regulatory elements (summarized by Virgilio et al., 1998