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STAG3 Polyclonal Antibody, 20ul Thermo Mix The galectins have been implicated

SKU: 93440408205

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PLN111.00 PLN146.00

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STAG3 Polyclonal Antibody, 20ul Thermo Mix The galectins have been implicatedThe stromal antigen 3 encoded by STAG3 is expressed in the nucleus and is a subunit of the cohesin complex which regulates the cohesion of sister chromatids during cell division. A mutation in this gene is associated with premature ovarian failure. Alternate splicing results in multiple transcript variants encoding distinct isoforms. This gene has multiple pseudogenes.

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Description

The galectins have been implicated in many essential functions including development

Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and trace-amine receptor activity

The encoded protein is a transcriptional activator that is required for normal development of the central nervous system

Deletion of TCF3 or diminished activity of the encoded protein may play a role in lymphoid malignancies

ABL1 has been found fused to a variety of translocation partner genes in various leukemias

STAG3 Polyclonal Antibody, 20ul Thermo Mix The galectins have been implicatedThe stromal antigen 3 encoded by STAG3 is expressed in the nucleus and is a subunit of the cohesin complex which regulates the cohesion of sister chromatids during cell division. A mutation in this gene is associated with premature ovarian failure. Alternate splicing results in multiple transcript variants encoding distinct isoforms. This gene has multiple pseudogenes.

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