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ARK-1 Polyclonal Antibody, 50ul[BT-AP00611] Cell Culture Flasks This protein is expressed at

SKU: 93161076719

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SEK185.00 SEK206.00

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ARK-1 Polyclonal Antibody, 50ul[BT-AP00611] Cell Culture Flasks This protein is expressed atThe protein encoded by AURKA is a cell cycle regulated kinase that appears to be involved in microtubule formation and or stabilization at the spindle pole during chromosome segregation. The encoded protein (aurora kinase A) is found at the centrosome in interphase cells and at the spindle poles in mitosis. AURKA may play a role in tumor development and progression. A processed pseudogene of AURKA has been found on chromosome 1, and an unprocessed

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Description

This protein is expressed at high levels on the apical side of mature enterocytes in the small intestine

in some cases accompanied by neurological abnormalities

An important paralog of this gene is TBC1D10C

Multiple alternatively spliced variants| encoding the same protein| have been identified

Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP

ARK-1 Polyclonal Antibody, 50ul[BT-AP00611] Cell Culture Flasks This protein is expressed atThe protein encoded by AURKA is a cell cycle regulated kinase that appears to be involved in microtubule formation and or stabilization at the spindle pole during chromosome segregation. The encoded protein (aurora kinase A) is found at the centrosome in interphase cells and at the spindle poles in mitosis. AURKA may play a role in tumor development and progression. A processed pseudogene of AURKA has been found on chromosome 1, and an unprocessed

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