SLP-76(Phospho-Tyr145) Rabbit Polyclonal Antibody, 100ul Sampling Tubes Mutations in NCF1 have been

Mutations in NCF1 have been associated with chronic granulomatous disease

using a separate promoter in an intron in the 3' region

The encoded protein (A-kinase anchoring protein 1) binds to type I and type II regulatory subunits of PKA and anchors them to the mitochondrion

the number of sodium pumps transported to the plasma membrane

NOTCH4 encodes a member of the NOTCH family of proteins

SLP-76(Phospho-Tyr145) Rabbit Polyclonal Antibody, 100ul Sampling Tubes Mutations in NCF1 have beenSLP 76 was originally identified as a substrate of the ZAP 70 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T cell line Jurkat. The SLP 76 locus has been localized to human chromosome 5q33 and the gene structure has been partially characterized in mice. The human and murine cDNAs both encode 533 amino acid proteins that are 72% identical and comprised of three modular domains. The NH2 terminus contains an acidic