CD59 Polyclonal Antibody, 50ul[BT-AP01752] Miscellaneous However the human cDNA encoding

However the human cDNA encoding a 700 amino acid protein with a peroxisomal targeting C-terminal tripeptide S-K-L was isolated and is thought to be expressed under special conditions such as specific developmental stages or in a tissue specific manner in tissues that have not yet been examined

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There are multiple pseudogenes for this gene on chromosomes 9

The centromere is a specialized chromatin domain

one of which encodes a high-mobility group protein

CD59 Polyclonal Antibody, 50ul[BT-AP01752] Miscellaneous However the human cDNA encodingApoptosis antagonizing transcription factor encoded by AATF was identified on the basis of its interaction with MAP3K12 DLK, a protein kinase known to be involved in the induction of cell apoptosis. AATF product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of AATF interfered with MAP3K12 induced