EGFR Monoclonal Antibody(1B10), 50ul Cell Culture Cadherin domains occur as repeats

Cadherin domains occur as repeats in the extracellular region and are thought to contribute to the sorting of heterogeneous cell types and the maintenance of orderly structures such as epithelium

particularly

|Contains 2 phorbol-ester/DAG-type zinc fingers

It is also found in the nucleus

This gene encodes a protein that contains a WD-40 domain| and is thought to be involved in diphthamide biosynthesis

EGFR Monoclonal Antibody(1B10), 50ul Cell Culture Cadherin domains occur as repeatsThe protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.