Human E3 Ubiquitin-protein Ligase Dtx3L, DTX3L ELISA Kit, 96T PCR Series Also able to hydrolyze 2'-3'-cGAMP

Also able to hydrolyze 2'-3'-cGAMP (cyclic GMP-AMP)

The encoded protein is localized to lipid rafts of the endoplasmic reticulum and plays a critical role in inositol 1|4|5-trisphosphate (IP3) signaling by mediating ER-associated degradation of activated IP3 receptors

The gene product may play a role in degradation and maturation of tachykinins

The encoded protein forms a dimer with an alpha v chain and this heterodimer can bind to ligands like fibronectin and transforming growth factor beta 1

A processed pseudogene of ESRRA is located on chromosome 13q12

Human E3 Ubiquitin-protein Ligase Dtx3L, DTX3L ELISA Kit, 96T PCR Series Also able to hydrolyze 2'-3'-cGAMP