AP1B1 Rabbit Polyclonal Antibody, 50ul Dry Bath Centromere protein A is proposed

Centromere protein A is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle

and bind SHP2 tyrosine phosphatase and GRB2 adapter protein

subcellular location:Enriched in lipid rafts

Chromosomal rearrangements and altered expression of this gene have been implicated in breast cancer

which is known for regulating the energy balance of mitochondria under stress

AP1B1 Rabbit Polyclonal Antibody, 50ul Dry Bath Centromere protein A is proposedAdaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as one of the large subunits of this complex