p53 Rabbit Polyclonal Antibody, 50ul[BT-AP11728] Serum SMAD family member 1 encoded

SMAD family member 1 encoded by SMAD1 belongs to the SMAD

UBTF encodes a member of the HMG-box DNA-binding protein family

and two phosphorylatable regulatory light chains

the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex

Mutations in this gene are associated with methylmalonic aciduria

p53 Rabbit Polyclonal Antibody, 50ul[BT-AP11728] Serum SMAD family member 1 encodedThis gene encodes a tumor suppressor protein containing transcriptional activation DNA binding and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes thereby inducing cell cycle arrest apoptosis senescence DNA repair or changes in metabolism. Mutations in this gene are associated with a variety of human cancers including hereditary cancers such as Li Fraumeni syndrome. Alternative