GASP-1 Polyclonal Antibody, 100ul 3D Culture Acrosin binding protein is located

Acrosin binding protein is located in the sperm acrosome and is thought to function as a binding protein to proacrosin for packaging and condensation of the acrosin zymogen in the acrosomal matrix

The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad17

They may thus play an important role during growth and development

The protein is localized to the nuclear rim and is an essential component of the nuclear pore complex (NPC)

Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1)

GASP-1 Polyclonal Antibody, 100ul 3D Culture Acrosin binding protein is locatedGPRASP1 (G protein coupled receptor associated sorting protein 1) encodes a member of the GPRASP (G protein coupled receptor associated sorting protein) family. The protein may modulate lysosomal sorting and functional down regulation of a variety of G protein coupled receptors. It targets receptors for degradation in lysosomes. The receptors interacting with this sorting protein include D2 dopamine receptor (DRD2), delta opioid receptor (OPRD1), beta