BUB1B Polyclonal Antibody, 50ul Gene Synthesis and is associated with hearing

and is associated with hearing loss

Diseases associated with PGLS include lymphatic system disease

but their full-length natures have not been determined

The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export

A promoter region between this gene and the 5'-adjacent RGS19 (regulator of G-protein signaling 19) gene on the opposite strand functions bi-directionally as a core-promoter for both genes

BUB1B Polyclonal Antibody, 50ul Gene Synthesis and is associated with hearingThis gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase promoting complex cyclosome (APC C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer.