TRI66 Rabbit Polyclonal Antibody, 20ul Erlenmeyer Flasks Pituitary tumor-transforming 1 is a

Pituitary tumor-transforming 1 is a homolog of yeast securin proteins

and maps to human chromosome 18q22

This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway

Three transcript variants encoding different isoforms have been found for PLA1A

endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane

TRI66 Rabbit Polyclonal Antibody, 20ul Erlenmeyer Flasks Pituitary tumor-transforming 1 is a