Cdc25A(Phospho Ser178) Polyclonal Antibody, 50ul Sampling Tubes and thereby enhances TGF-beta target-gene

and thereby enhances TGF-beta target-gene transcription

Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain

The protein encoded by this gene belongs to the ubiquitin-specific proteases (UBP) family of enzymes that cleave ubiquitin from ubiquitinated protein substrates

The PeBoW complex also associates with the 66S pre-ribosome

This gene encodes a highly conserved protein involved in the preassembly of dynein arm complexes which power cilia

Cdc25A(Phospho Ser178) Polyclonal Antibody, 50ul Sampling Tubes and thereby enhances TGF-beta target-geneCDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated.