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NEK1 Polyclonal Antibody, 50ul Yeast Expression This gene maps in a

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NEK1 Polyclonal Antibody, 50ul Yeast Expression This gene maps in aThe protein encoded by this gene is a serine threonine kinase involved in cell cycle regulation. The encoded protein is found in a centrosomal complex with FEZ1, a neuronal protein that plays a role in axonal development. Defects in this gene are a cause of polycystic kidney disease (PKD). Several transcript variants encoding different isoforms have been found for this gene.

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Description

This gene maps in a region that contains the BRCA1 locus which confers susceptibility to breast and ovarian cancer

This gene is located adjacent to the imprinted domain in the Prader-Willi syndrome deletion region of chromosome 15

and represses their transcriptional activity

are structurally related to ubiquitin (MIM 191339) and can be ligated to target proteins in a similar manner as ubiquitin

like all members of the GPCR superfamily

NEK1 Polyclonal Antibody, 50ul Yeast Expression This gene maps in aThe protein encoded by this gene is a serine threonine kinase involved in cell cycle regulation. The encoded protein is found in a centrosomal complex with FEZ1, a neuronal protein that plays a role in axonal development. Defects in this gene are a cause of polycystic kidney disease (PKD). Several transcript variants encoding different isoforms have been found for this gene.

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