Jagged1 Polyclonal Antibody, 20ul[BT-AP10553] Dry Bath The chromosomal rearrangements are the

The chromosomal rearrangements are the most common genetic alterations in this gene

Previously| this gene had an official symbol of SLC23A2

The protein encoded by ELAC2 (elaC ribonuclease Z 2) has a C-terminal domain with tRNA processing endoribonuclease activity

It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway

This gene encodes a homeobox and paired domain-containing protein that binds DNA and functions as a regulator of transcription

Jagged1 Polyclonal Antibody, 20ul[BT-AP10553] Dry Bath The chromosomal rearrangements are theThe jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.