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TRIB3 Polyclonal Antibody, 50ul Pathway and Network Analysis UNC5A belongs to a family

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TRIB3 Polyclonal Antibody, 50ul Pathway and Network Analysis UNC5A belongs to a familyThe protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF kappaB. The encoded protein is a negative regulator of NF kappaB and can also sensitize cells to TNF and TRAIL induced apoptosis. In addition, this protein can negatively regulate the cell survival serine threonine kinase AKT1. Differential promoter usage and alternate splicing result in multiple transcript variants.

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Description

UNC5A belongs to a family of netrin-1 (MIM 601614) receptors thought to mediate the chemorepulsive effect of netrin-1 on specific axons

exhibits antimicrobial activities against bacteria and induces immunomodulatory activities

C1q is composed of 18 polypeptide chains: six A-chains

is present on monocytes

and this interaction is important to proper microtubule function in the developing cortex

TRIB3 Polyclonal Antibody, 50ul Pathway and Network Analysis UNC5A belongs to a familyThe protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF kappaB. The encoded protein is a negative regulator of NF kappaB and can also sensitize cells to TNF and TRAIL induced apoptosis. In addition, this protein can negatively regulate the cell survival serine threonine kinase AKT1. Differential promoter usage and alternate splicing result in multiple transcript variants.

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