RSH4A Rabbit Polyclonal Antibody, 50ul Custom Peptide Synthesis The TERF1 interacting nuclear factor

The TERF1 interacting nuclear factor 2 encoded by TINF2 is a critical part of shelterin

It is located within the 11q23

TINF2 encodes one of the proteins of the shelterin

|subcellular location:Isoform 1 and isoform 2 show a lower surface expression when expressed in cells

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RSH4A Rabbit Polyclonal Antibody, 50ul Custom Peptide Synthesis The TERF1 interacting nuclear factorThis gene encodes a protein that appears to be a component the radial spoke head as determined by homology to similar proteins in the biflagellate alga Chlamydomonas reinhardtii and other ciliates. Radial spokes which are regularly spaced along cilia sperm and flagella axonemes consist of a thin 'stalk' and a bulbous 'head' that form a signal transduction scaffold between the central pair of microtubules and dynein. Mutations in this gene cause