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IκB-alpha Polyclonal Antibody, 50ul[BT-AP06782] Culture Plate Inserts and contains two phopshotyrosine-binding domains

SKU: 8961703950

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IκB-alpha Polyclonal Antibody, 50ul[BT-AP06782] Culture Plate Inserts and contains two phopshotyrosine-binding domainsThis gene encodes a member of the NF kappa B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell

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Description

and contains two phopshotyrosine-binding domains (PTB1 and PTB2)

which is a member of the claudin family

Mutations in this gene are associated with microvillous inclusion disease

This gene is expressed in the inner ear and bladder epithelium

The activity of this protein is sensitive to phospholipids

IκB-alpha Polyclonal Antibody, 50ul[BT-AP06782] Culture Plate Inserts and contains two phopshotyrosine-binding domainsThis gene encodes a member of the NF kappa B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell

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