APC5 Polyclonal Antibody, 100ul Cell Dissociation and its SH2 domain binds

and its SH2 domain binds tyrosine phosphorylated sequences

HeLa (cervix epithelioid carcinoma)

Contains 11 LRR (leucine-rich) repeats

and a tyrosine kinase (TK) domain within the cytoplasmic domain

Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis

APC5 Polyclonal Antibody, 100ul Cell Dissociation and its SH2 domain bindsANAPC5 encodes a tetratricopeptide repeat containing component of the anaphase promoting complex cyclosome (APC C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B type cyclins for 26S proteasome mediated degradation through ubiquitination. The encoded protein (anaphase promoting complex subunit 5) is required for the proper ubiquitination function of APC C and for the