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UHRF1 Polyclonal Antibody, 100ul Filtration Defects in this gene also

SKU: 89156798136

4.2
SEK123.75 SEK173.75

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UHRF1 Polyclonal Antibody, 100ul Filtration Defects in this gene alsoUHRF1 encodes a member of a subfamily of RING finger type E3 ubiquitin ligases. E3 ubiquitin protein ligase UHRF1binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1 S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53 dependent

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Description

Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome

including one with a novel exon that is generated by RNA editing

BMP antagonists contain cystine knots and typically form homo- and heterodimers

and it can interact with CT120

The encoded protein may be found in the Golgi apparatus and may be involved in the production of polysialic acid

UHRF1 Polyclonal Antibody, 100ul Filtration Defects in this gene alsoUHRF1 encodes a member of a subfamily of RING finger type E3 ubiquitin ligases. E3 ubiquitin protein ligase UHRF1binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1 S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53 dependent

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