NF-1 Polyclonal Antibody, 100ul Mammalian Expression and Paget disease of bone

and Paget disease of bone

The protein encoded by this gene contains a RING finger domain

Reductions in the expression of this gene have been associated with Down's syndrome and Alzheimer's disease

suggesting that it may be a good candidate for the del(5q) tumor suppressor gene

Certain mutations in this gene resulting in a functionally inadequate enzyme are associated with a rare genetic disorder causing nonspherocytic hemolytic anemia

NF-1 Polyclonal Antibody, 100ul Mammalian Expression and Paget disease of boneNFIA encodes a member of the NF1 (nuclear factor 1) family of transcription factors. Multiple transcript variants encoding different isoforms have been found for this gene.