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PARL Monoclonal Antibody, 100ul Mammalian Expression This enzyme is an ADP-ribose

SKU: 88618715812

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PARL Monoclonal Antibody, 100ul Mammalian Expression This enzyme is an ADP-riboseThis gene encodes a member of the rhomboid family of intramembrane serine proteases that is localized to the inner mitochondrial membrane. The encoded protein regulates mitochondrial remodeling and apoptosis through regulated substrate proteolysis. Proteolytic processing of the encoded protein results in the release of a small peptide, P beta, which may transit to the nucleus. Mutations in this gene may be associated with Parkinson's disease.

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Description

This enzyme is an ADP-ribose pyrophosphatase that catalyzes the hydrolysis of ADP-ribose to AMP and ribose-5-P

This protein and other members of the family are localized to synaptic vesicles and may function in the regulation of vesicle trafficking and exocytosis

plasma cholesteryl ester transfer protein (CETP)

MDK has been targeted as a therapeutic for a variety of different disorders

disease:Defects in MT-ATP6 are a cause of infantile bilateral striatal necrosis

PARL Monoclonal Antibody, 100ul Mammalian Expression This enzyme is an ADP-riboseThis gene encodes a member of the rhomboid family of intramembrane serine proteases that is localized to the inner mitochondrial membrane. The encoded protein regulates mitochondrial remodeling and apoptosis through regulated substrate proteolysis. Proteolytic processing of the encoded protein results in the release of a small peptide, P beta, which may transit to the nucleus. Mutations in this gene may be associated with Parkinson's disease.

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