Tuberin(Phospho Thr1462) Polyclonal Antibody, 100ul Plates & Dishes Individuals with the A

Individuals with the A

This protein is essential for mediating responses to IL12 in lymphocytes| and regulating the differentiation of T helper cells

45 µm Pore Size and PES Membrane

Mutations in NR3C are associated with generalized glucocorticoid resistance

Amplification and/or overexpression of this gene has been reported in numerous cancers| including breast and ovarian tumors

Tuberin(Phospho Thr1462) Polyclonal Antibody, 100ul Plates & Dishes Individuals with the AMutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.