ECM1 Polyclonal Antibody, 50ul Immunoassays Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory

Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase is a membrane-associated kinase that negatively regulates the G2/M transition of the cell cycle by phosphorylating and inactivating cyclin-dependent kinase 1

but is not responsible for this disease

This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones

FOXL1 encodes a member of the forkhead/winged helix-box (FOX) family of transcription factors

MIM 611054) for background on liprins

ECM1 Polyclonal Antibody, 50ul Immunoassays Membrane-associated tyrosine- and threonine-specific cdc2-inhibitoryECM1 encodes a soluble protein that is involved in endochondral bone formation, angiogenesis, and tumor biology. It also interacts with a variety of extracellular and structural proteins, contributing to the maintenance of skin integrity and homeostasis. Mutations in this gene are associated with lipoid proteinosis disorder (also known as hyalinosis cutis et mucosae or Urbach Wiethe disease) that is characterized by generalized thickening of skin,