Rat Matrix Metalloproteinase 2, MMP2 ELISA Kit , 96T Drug Development and Evaluation May play an important role

May play an important role in cell proliferation and/or anti-apoptosis

Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1

Defects in this gene are associated with Charcot-Marie-Tooth disease type 1D (CMT1D)

eosinophil migration

translocates into the mitochondria where it promotes mtDNA transcription (PubMed: 23283301)

Rat Matrix Metalloproteinase 2, MMP2 ELISA Kit , 96T Drug Development and Evaluation May play an important roleUbiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly Leu bond. Appears to have a role in myocardial cell death